6 Month Update The goal of our pilot project is to identify the role that the G protein-coupled estrogen receptor (GPER) plays in the development and progression of kidney disease […]
6 Month Update Aim 1. Determine the viral infection history of T1D patients compared to healthy controls. Methods: We designed 15,000 oligonucleotides covering all 6 of the insulin carrying viruses and […]
6 Month Update Our studies have identified a novel pathway consisting of two receptors, LGR4 (Leucine-rich repeat-containing G-protein-coupled receptor 4), a positive, and RANK (Receptor Activator of NFκB), a negative regulator, whose […]
6 Month Update The primary objective of this DRC-funded project is to investigate the role of PD-L1 molecules in beta cells under stress conditions, hypothesizing that they may increase to […]
Project Description Type 1 diabetes (T1D) is caused by the autoimmune destruction of insulin-producing β-cells while leaving behind other pancreatic islet cell types. Over the past decade, research has demonstrated […]
Project Description The immune system, which normally protects us from infection, can improperly attack the insulin-producing beta cells in the pancreatic islets, which leads to type 1 diabetes (T1D). Often, […]
Project Description Type 1 Diabetes is an autoimmune disease which involves both environmental and genetic drivers. It is thought that genetic mutations that contribute to T1D impact the function of […]
Project Description In Type 1 Diabetes (T1D), the immune system mistakenly attacks the cells in the pancreas that produce insulin, leaving the body unable to regulate blood sugar levels properly. […]
Project Description Type 1 diabetes (T1D) occurs due to a loss of insulin producing beta cells in the pancreas. The hormone insulin regulates blood glucose levels which is vital for […]
Project Description Stem cells offer new hopes for cell replacement therapies to cure Type 1 Diabetes (T1D), an autoimmune disease causing the loss of insulin-producing b-cells. Yet, despite promising results from […]
Up to $75,000 is available for each research project we support, highlighting the urgent need for continued investigation into Type 1 Diabetes. This funding is vital for uncovering new treatments and ultimately a cure, offering hope to millions affected by this condition. Through dedicated research, we aim to improve lives and change the future of Type 1 Diabetes care.
#InnovativeDiabetesResearch
