DRC & Research News

This page shares the latest news in T1D research and DRC’s community.

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Connect For A Cure: November 2020 Newsletter

DRC has distributed over $400,000 to research projects like Dr. Hughes’s and Dr. Racine’s in 2020 alone! We have received three times the average amount of applications for funding of new projects over the past couple of months. View our “Support a Project” page to see what other research projects we are currently funding by clicking here. Take a look at our newsletter to see how great DRC’s 3rd Annual Dance for Diabetes Virtual Party was! Thank you to everyone who participated and donated to the event, DRC could not do what it does without the generous support of its donors and community.

Click this link to view our November newsletter that we mailed out previously this month about what we’ve been up to and the impact we are making together. It takes a community to connect for a cure!

 

 

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Connect For A Cure: June 2020 Newsletter

The importance of research has been highlighted during this pandemic and our early-career scientists continue their ground-breaking, peer-reviewed research. Since November, we’ve funded 8 new research projects. Thank you for your support and for being a part of the DRC community.

Click on the link below to read more about what we’ve been up to and the impact we are making together. It takes a community to connect for a cure!

June 2020 Newsletter

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OUR PROJECTS

See our approved research projects and campaigns.

Role of the integrated stress response in type 1 diabetes pathogenesis
In individuals with type 1 diabetes (T1D), the insulin-producing beta cells are spontaneously destroyed by their own immune system. The trigger that provokes the immune system to destroy the beta cells is unknown. However, accumulating evidence suggest that signals are perhaps first sent out by the stressed beta cells that eventually attracts the immune cells. Stressed cells adapt different stress mitigation systems as an adaptive response. However, when these adaptive responses go awry, it results in cell death. One of the stress response mechanisms, namely the integrated stress response (ISR) is activated under a variety of stressful stimuli to promote cell survival. However, when ISR is chronically activated, it can be damaging to the cells and can lead to cell death. The role of the ISR in the context of T1D is unknown. Therefore, in this DRC funded study, we propose to study the ISR in the beta cells to determine its role in propagating T1D.
Wearable Skin Fluorescence Imaging Patch for the Detection of Blood Glucose Level on an Engineered Skin Platform
zhang
A Potential Second Cure for T1D by Re-Educating the Patient’s Immune System
L Ferreira
Validating the Hypothesis to Cure T1D by Eliminating the Rejection of Cells From Another Person by Farming Beta Cells From a Patient’s Own Stem Cells
Han Zhu
Taming a Particularly Lethal Category of Cells May Reduce/Eliminate the Onset of T1D
JRDwyer 2022 Lab 1
Can the Inhibition of One Specific Body Gene Prevent Type 1 Diabetes?
Melanie
Is Cholesterol Exacerbating T1D by Reducing the Functionality and Regeneration Ability of Residual Beta Cells?
Regeneration Ability of Residual Beta Cells
A Call to Question… Is T1D Caused by Dysfunctionality of Two Pancreatic Cells (β and α)?
Xin Tong
Novel therapy initiative with potential path to preventing T1D by targeting TWO components of T1D development (autoimmune response and beta-cell survival)
flavia pecanha