DRC & Research News

This page shares the latest news in T1D research and DRC’s community.

Get the most recent diabetes research news, delivered straight to your inbox

Sleep Disturbances Common with Type 1 Diabetes -Photo by Marcus Aurelius from Pexels

Sleep Disturbances with Type 1 Diabetes

Sleep Disturbances Common with T1D

Type 1 diabetes is a disease that must be monitored around the clock. When children are awake, it is easier to tell when blood sugar may be spiking too high or dropping too low. At night, this is more challenging, and it is essential to continue testing blood sugar levels to stay within the target range and administer insulin as necessary.

Children typically rely on their parents to manage their diabetes and monitor blood sugar, whether done manually or through a continuous glucose monitor (CGM). A recent study found that children who use a CGM often sleep better at night, but it is their parents who have more disturbances in their sleep due to reacting to CGM data.

As part of a larger study, researchers evaluated the sleep quality of 46 parents of children with type 1 diabetes. The children were between the ages of 2 and 5, and some used CGMs while others did not. Parents reported on the time their children went to bed, woke up, and how long they slept. The average was 10.4 hours per night. Also, all 11 families who used CGMs wore accelerometers that tracked their sleep patterns for a minimum of four nights. The accelerometer showed an average of 9.8 hours of sleep per night for children.

According to the study, “Among the full cohort, 63% of parents reported checking their child’s blood glucose levels at least a few nights per week. Parents of children using CGMs reported a higher frequency of nighttime blood glucose monitoring compared with parents of children without a CGM.”

The percentage of parents who experienced sleep disturbances concerning blood glucose monitoring was noticeably higher than the percentage of children, at 78.3% and 17% respectively. Parents of children with CGMs reported higher levels of sleep disturbance, especially when the child’s diabetes was more difficult to manage. Additional research with a larger group of participants across a longer period of time is necessary to better understand the impact of diabetes management on sleep for parents and children.

It is important for physicians to keep in mind not just the impact a CGM or other device could have on the child’s health and quality of life, but also on the parent. Parents benefit from having proper support systems in place and information to help them cope with the challenges of managing their child’s type 1 diabetes.

Diabetes Research Connection, though not involved in this study, is committed to supporting early-career scientists focused on studying type 1 diabetes and ways to improve prevention, treatment, and quality of life, as well as one day finding a cure. One hundred percent of donations go directly to the scientists for their research. To learn more about current projects and how to help, visit https://diabetesresearchconnection.org.

Learn More +
Diabetes Researching

Three Words that Changed My Life Forever…Type 1 Diabetes

National Tell a Story Day

I will never forget April 30, 2003, the day my life changed forever. My mom picked me up from school and asked, “How many times did you pee today, Hannah?” It’s a question she’s been asking frequently. I thought I might get in trouble if I told her the truth, so I said only twice.

We drove away and suddenly I could tell we were driving in the direction of my pediatrician’s office, not home. When I noticed my dad’s car in the parking lot, I knew it was not a routine visit, something was off. I was rushed inside, weight taken, vitals checked and then the dreaded blood test.

After some time passed, the doctor came in and told us to sit down. He started speaking to my parents about how all the signs; my drastic weight loss, the number of times I went to the bathroom and the amount of liquids I consumed daily confirmed what my parents already thought, I have type 1 diabetes (T1D).

I was diagnosed with T1D 17 years ago at the age of 7. My childhood was spent counting carbs, making sure I had all my supplies every time I left the house, worrying about ketoacidosis, low blood sugar and having to go to the hospital.

After my diagnosis, life was hard. I was not allowed to go on field trips, kids teased me and said I had “cooties” (the simple term for contagious) and I could not enjoy food or life the same way I did before. It was not until that summer that things started getting better.

My dad found a camp for kids with T1D and booked a weekend family trip. The first thing I did when I got there was learn how to give myself insulin shots. I wasn’t scared; I was excited to gain some control back. My parents found other parents who were worried about this new predicament as well and talked about tips for management and how to cope.

I never really had hope growing up that there would be a cure during my lifetime…until now!

As the Development Assistant at the Diabetes Research Connection (DRC), I see first-hand the innovative research being funded and it gives me hope.

Now, I have hope that this disease WILL be eliminated, and I WILL be alive when the cure is discovered.

~ Written by Hannah Gebauer

Learn More +


See our approved research projects and campaigns.

Role of the integrated stress response in type 1 diabetes pathogenesis
In individuals with type 1 diabetes (T1D), the insulin-producing beta cells are spontaneously destroyed by their own immune system. The trigger that provokes the immune system to destroy the beta cells is unknown. However, accumulating evidence suggest that signals are perhaps first sent out by the stressed beta cells that eventually attracts the immune cells. Stressed cells adapt different stress mitigation systems as an adaptive response. However, when these adaptive responses go awry, it results in cell death. One of the stress response mechanisms, namely the integrated stress response (ISR) is activated under a variety of stressful stimuli to promote cell survival. However, when ISR is chronically activated, it can be damaging to the cells and can lead to cell death. The role of the ISR in the context of T1D is unknown. Therefore, in this DRC funded study, we propose to study the ISR in the beta cells to determine its role in propagating T1D.
Wearable Skin Fluorescence Imaging Patch for the Detection of Blood Glucose Level on an Engineered Skin Platform
A Potential Second Cure for T1D by Re-Educating the Patient’s Immune System
L Ferreira
Validating the Hypothesis to Cure T1D by Eliminating the Rejection of Cells From Another Person by Farming Beta Cells From a Patient’s Own Stem Cells
Han Zhu
Taming a Particularly Lethal Category of Cells May Reduce/Eliminate the Onset of T1D
JRDwyer 2022 Lab 1
Can the Inhibition of One Specific Body Gene Prevent Type 1 Diabetes?
Is Cholesterol Exacerbating T1D by Reducing the Functionality and Regeneration Ability of Residual Beta Cells?
Regeneration Ability of Residual Beta Cells
A Call to Question… Is T1D Caused by Dysfunctionality of Two Pancreatic Cells (β and α)?
Xin Tong
Novel therapy initiative with potential path to preventing T1D by targeting TWO components of T1D development (autoimmune response and beta-cell survival)
flavia pecanha