DRC & Research News

This page shares the latest news in T1D research and DRC’s community.

Get the most recent diabetes research news, delivered straight to your inbox

Exploring the Impact of Type 1 Diabetes on COVID-19

For the past several months, the world has been struggling to contain the spread of COVID-19 and effectively treat patients diagnosed with this disease. It is a new strain of coronavirus that researchers continue to learn more about every day. One thing that is known about the virus is that individuals with underlying health conditions are at increased risk of developing severe illness and complications.

One such underlying health condition that researchers are paying closer attention to is type 1 diabetes (T1D). Preliminary research from small studies appear to show that individuals with T1D are at increased risk of poorer health outcomes than those with type 2 diabetes (T2D) or no history of diabetes. A recent study of 64 individuals with T1D and confirmed or suspected COVID-19 in the United States found that “more than 50% of all cases reported hyperglycemia, and nearly one-third of patients experienced DKA.” Both hyperglycemia and diabetic ketoacidosis (DKA) can be life-threatening conditions if not properly treated in time.

Furthermore, research released from the United Kingdom’s National Health Service (NHS) revealed that hospitalized individuals with T1D are significantly more likely to die from COVID-19 than those with T2D. Scientists believe that hyperglycemia may enhance the immune system’s overresponse thereby exacerbating the impact of severe infections.

Being hospitalized can make it more difficult for individuals with T1D to maintain glycemic control because their body is already trying to fight off infection, and they may not have the mental clarity or ability to effectively monitor their own blood sugar. Diabetes Research Connection (DRC) sponsored a study by Addie Fortmann, Ph.D., regarding the use of continuous glucose monitors (CGMs) in hospital settings, which found that these devices were pivotal to glycemic control. As a result, Scripps deployed this technology across all of their hospitals to better support diabetes management.

But not every hospital in the United States allows patients to use their CGM while admitted, and not all staff is adequately trained in diabetes care. This can complicate things for patients struggling with T1D as well as COVID-19 and contribute to poorer health outcomes. Not only are patients fighting against the effects of COVID-19 including fever, shortness of breath, dry cough, nausea, body aches, and fatigue, if their blood sugar should go too high or too low, this can add to more symptoms and complications. In both patients with confirmed and suspected COVID-19 as well as T1D, DKA was the most prevalent adverse outcome.

It is essential that attention is given to managing underlying conditions such as diabetes in order to provide more effective treatment tailored to patient needs. Since 2012, the DRC has been providing critical funding for early-career scientists pursuing novel, peer-reviewed research related to type 1 diabetes. This work is essential to advancing understanding of the disease, improving prevention strategies and treatment options, minimizing complications, enhancing quality of life, and working toward a cure. Learn more about current projects and how to support these efforts by visiting https://diabetesresearchconnection.org.

Learn More +

Type 1 Diabetes and the Coronavirus (COVID-19)

Those with Type 1 Diabetes (T1D) are members of an exclusive club which is more vulnerable to the effects of the Coronavirus (COVID-19), once it is contracted. Click here to learn more. We encourage you to follow the World Health Organization’s protective recommendations.

While T1D‘s are not at a greater risk of contracting the disease, it is important to take precautionary measures. These include measuring your blood glucose levels frequently and keeping them in the normal range. This will help ensure greater resistance and a faster recovery. More frequent monitoring of ketones is critical, especially if your blood glucose is elevated due to sickness, cold therapeutics containing sugar or syrup and inactivity. Steroidal decongestants are also likely to increase your blood glucose levels. Diabetic ketoacidosis (DKA) may exhibit flu-like symptoms, which is why it is important to measure ketones with test strips available from your local pharmacy or online. Additional amounts of insulin may be required under these circumstances. Contact your physician(s) immediately if you have been exposed to the virus or have symptoms.

Be sure to stock an adequate supply (a minimum of two weeks) of all your medications. For more advice managing T1D during this pandemic, please visit: https://www.jdrf.org/coronavirus/.

For the latest updates on the global impact of COVID-19 go to: https://www.worldometers.info/coronavirus/.

Learn More +

Unlimited access to all the essential project updates latest diabetes research news, and more.