We were established in 2012 by five proponents of diabetes research, and our visionis to support innovative scientific inquiry until type 1 diabetes is eliminated. However, we can’t do it without the valuable contributions from our donors and supporters.
Want to get involved in type 1 diabetes research? Read below to find out how you can make a difference.
Help Fund Type 1 Diabetes Research
Many scientific breakthroughs come from the inventiveness of early-career scientists. Unfortunately, mainstream funding rarely goes to support these innovative researchers, with 97% of funding for type 1 diabetes research going to established scientists. This means that it’s often hard for new diabetes research ideas to get off the ground.
That’s where the Diabetes Research Connection comes in; we grant up to $50,000 to support type 1 diabetes research from early-career scientists.
Consider financially supporting one of the following type 1 diabetes research projects.
Gene-Specific Models and Therapies for Type 1 Diabetes
Multiple genetic factors contribute to type 1 diabetes, but researchers are limited to using mice models with one genetic profile. Jeremy Racine, Ph.D. of The Jackson Laboratory in Bar Harbor, Maine is working to create a new mouse model with a genetic blank slate for insertion of relevant HLA gene variants that are related to the development of diabetes. Additionally, he plans to test a therapy that has been specifically designed for a diabetes susceptible gene variation known as HLA-A*0201 (A2.1). Click here to support this project.
Identify Biomarkers for Susceptibility to Both Type 1 Diabetes and Mental Disorders
Recent studies have found that those with diabetes have a much higher rate of depression, and young people with type 1 diabetes have a much higher rate of suicide than their peers. Agata Jurcyzk, Ph.D., a research instructor at the University of Massachusetts Medical School, is working to identify genetic signatures in white blood cells that distinguish non-progressor T1D patients and T1D patients that progress to psychiatric illness. Click here to support this project.
Regrowth of Beta Cells with Small Molecule Therapy
Type 1 diabetes develops when beta cells are destroyed and the body can no longer produce enough insulin to convert the sugar we eat into energy. Peter Thompson, Ph.D., a researcher at the University of California San Francisco Diabetes Center, is working to identify new events during the progression to T1D in order to design new interventions that could prevent or reverse the progression to T1D. Click here to support this project.
Replacement Beta-Cells From An Unexpected Source
A cure for diabetes will involve replacing the insulin-producing beta cells that have been lost due to the disease. Joseph Lancman, Ph.D. of Sanford Burnham Prebys Medical Discovery Institute is researching to find a way to make in vivo cell lineage reprogramming safe and practical. This will make it possible to convert nearly any cell type into replacement beta cells, without removing them from the body. Click here to support this project.
Participate in Diabetes Research Studies
Diabetes Research Connection is currently partnering with four great research studies, but there are many more type 1 diabetes studies currently taking place. If you would like to get involved in these, consider participating in a type 1 diabetes clinical research study. We suggest checking out Type 1 Diabetes TrialNet.
TrialNet is a network of researchers seeking to prevent, delay or reverse the progression of type 1 diabetes. The organization works with 18 Clinical Centers in the U.S. and across the globe, and also partners with more than 150 medical centers and doctors’ offices.
Studies are available for those recently diagnosed with Type 1 diabetes, as well as those who have relatives with type 1 diabetes who are at a greater risk of developing the disease. You’ll need to participate in a screening to find out if you are eligible to join a TrialNet study.
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