DRC-Funded Discovery Reaches Major Milestones
This spring, Sana Biotechnology and Mayo Clinic announced a strategic collaboration to accelerate the development of SC451, an investigational stem cell-derived pancreatic islet cell therapy for type 1 diabetes. The […]
12 Month Update: Dr. Leonardo Ferreira
This project focused on engineering primary human regulatory T cells (Tregs) with a chimeric antigen receptor (CAR) to create a therapy for type 1 diabetes (T1D). These CAR Tregs can […]
6 Month Update: Dr. Leonardo Ferreira
6 Month Project Update This project focuses on using HLA-A2 CAR Tregs to protect HLA-A2-expressing human pancreatic islets from rejection in a humanized model of T1D, which this DRC grant […]
6 Month Update: Chaita Rao
6 Month Update The primary objective of this DRC-funded project is to investigate the role of PD-L1 molecules in beta cells under stress conditions, hypothesizing that they may increase to […]
6 Month Update: Joanna Filipowska
6 Month Update Our studies have identified a novel pathway consisting of two receptors, LGR4 (Leucine-rich repeat-containing G-protein-coupled receptor 4), a positive, and RANK (Receptor Activator of NFκB), a negative regulator, whose […]
6 Month Update: Aurelien Chuard
6 Month Project Update Aim 1. Determine the viral infection history of T1D patients compared to healthy controls. Methods: We designed 15,000 oligonucleotides covering all 6 of the insulin carrying viruses […]
6 Month Update: Carmen De Miguel
6 Month Project Update The goal of our pilot project is to identify the role that the G protein-coupled estrogen receptor (GPER) plays in the development and progression of kidney […]
From Seed Funding to the TEDx Stage: How One DRC-Funded Idea Is Advancing Toward a Cure for Type 1 Diabetes
In 2022, Diabetes Research Connection (DRC) awarded seed funding to Dr. Leonardo Ferreira for his project, “A Potential Second Cure for T1D by Re-Educating the Patient’s Immune System.” What began […]
NIH / NIDDK Presentation by DRC-funded researcher Dr. Leonardo Ferreira
We’re proud to share that DRC-funded researcher Dr. Leonardo Ferreira presented his exciting research findings at the January 14, 2025 NIH / NIDDK symposium honoring the 10-year anniversary of the Human Islet Research Network […]