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42 Factors that affect BG

42 Factors That Affect Blood Glucose

42 Factors That Affect Blood Glucose

Welcome to the Diabetes Research Connection, your trusted platform for valuable insights on diabetes management. Here we explore the above, “42 Factors That Affect BG”. Understanding these factors is crucial for anyone diagnosed with type 1 diabetes, health care providers, family, and friends about how our bodies regulate blood sugar levels.

To continue our mission of providing groundbreaking diabetes research and support, we invite you to make a difference. Please consider donating to DRC today. Your contribution directly impacts the advancement of diabetes research and the lives of those affected. Visit our website to learn more.

FOOD

1. Carbohydrate Quantity: Understanding carbohydrate intake is important for those with diabetes. Consider portion control and learn to read food labels. Remember, balancing carbohydrates with other food groups can help to stabilize blood sugar levels.

2. Carbohydrate Type: Opt for complex carbohydrates such as whole grains, fruits, and vegetables. These types are digested more slowly, preventing sudden blood sugar spikes.

3. Fat: Limit the amount of saturated and trans fats, which can lead to insulin resistance. Instead, choose heart-healthy unsaturated fats found in foods like avocados, nuts, and olive oil.

4. Protein: Include lean protein sources like chicken, fish, tofu, or lentils in your meals. Protein doesn’t raise blood sugar levels significantly and can help to keep you feeling satiated.

5. Caffeine: Monitor your body’s reaction to caffeine. Some people with diabetes find that caffeine causes blood sugar fluctuations. If that’s the case, reduce your caffeine intake.

6. Alcohol: If you choose to drink alcohol, do so in moderation and never on an empty stomach, as it can cause hypoglycemia. Choose low-sugar mixers to avoid blood sugar spikes.

7. Meal Timing: Regular meal and snack times can prevent blood sugar swings. Avoid skipping meals or eating late at night.

8. Dehydration: Make sure you’re drinking plenty of water throughout the day. Dehydration can negatively impact blood sugar levels.

9. Personal Microbiome: A healthy gut microbiome is believed to influence blood sugar control. Incorporate probiotic-rich foods like yogurt and fermented foods into your diet.

Understanding these ‘Food’ factors is key in diabetes management, but there’s more we can do together. Support the Diabetes Research Connection. Your donation makes a real difference in advancing diabetes care and knowledge.

MEDICATION

10. Medication Dose: Always take the correct dosage of your medications as prescribed by your healthcare provider. Any changes can cause fluctuations in your blood sugar levels.

11. Medication Timing: Take your medications at the same time every day. This consistency can greatly help in managing your blood sugar levels.

12. Medication Interactions: Be aware that certain medications can interact with your diabetes medication and impact your blood sugar levels. Always inform your healthcare provider about all the medications you’re taking.

13. Steroid Administration: Steroids can cause increased blood sugar levels. If prescribed a steroid, monitor your blood sugar closely and report any prolonged high readings to your healthcare provider.

14. Niacin (Vitamin B3): While niacin is important for overall health, it can raise blood sugar levels. Make sure you are getting an appropriate amount, and monitor your blood sugar if you take a supplement.

Managing medication is a vital part of diabetes control, but there’s more to explore and understand. Support DRC to deepen our collective knowledge and improve diabetes management strategies. Your contribution fuels groundbreaking research and aids in sharing essential information with the diabetes community. Join us in this important endeavor – visit our website to donate and help us make a lasting impact on diabetes.

ACTIVITY

15. Light Exercise: Regular light exercise, such as walking or gentle yoga, can help control blood sugar levels. Try to be active every day, but remember to monitor your blood sugar before, during, and after exercise.

16. High Intensity & Moderate Exercise: Exercise is key in diabetes management. High-intensity workouts like HIIT can improve insulin sensitivity, while moderate activities like brisk walking help regulate glucose levels. However, monitor your blood sugar before, during, and after exercise to avoid hyperglycemia or hypoglycemia. Always consult your healthcare provider before starting a new fitness regimen.

17. Level of Fitness/Training: Your overall fitness level can impact how your body uses insulin. Regular exercise can improve insulin sensitivity and help manage blood sugar levels. However, intense training may cause short-term blood sugar spikes, so monitor your levels and adjust your food intake or insulin dosage as needed.

18. Time of Day: Blood sugar can fluctuate throughout the day. Monitoring your blood sugar levels at various times can help you understand your body’s patterns and adjust your routine accordingly.

19. Food & Insulin Timing: For those taking insulin, coordinating your meals and insulin dosage is crucial. The timing will depend on your specific needs and the type of insulin you’re using.

Activity plays a significant role in diabetes management, but it’s just one piece of the puzzle. Support Diabetes Research Connection to empower further discovery and education in diabetes care. Your donation enables groundbreaking research and helps provide vital resources to those living with diabetes. Take action today by contributing to a cause that makes a real difference in the lives of those affected.

BIOLOGICAL

20. Too Little Sleep: Lack of sleep can disrupt your body’s insulin usage. Try to get at least 7-9 hours of sleep each night to help regulate your blood sugar.

21. Stress & Illness: Stress and illness can cause blood sugar levels to spike. Find stress management techniques that work for you, such as meditation or deep breathing exercises, and remember to monitor your blood sugar closely when you’re sick.

22. Recent Hypoglycemia: If you’ve recently experienced a bout of hypoglycemia, your body may release hormones that cause your blood sugar to rise. It’s important to monitor your blood sugar levels closely to prevent a “rebound” high.

23. During-Sleep Blood Sugars: Overnight blood sugar levels can fluctuate. Consider using a continuous glucose monitor to track your levels while you sleep.

24. Dawn Phenomenon: This is a surge in hormones that happens in the early morning, often causing an increase in blood sugar. Adjusting medication or food intake before bed can help manage this.

25. Infusion Set Issues: If you use an insulin pump, issues with the infusion set, like kinks or blockages, can affect insulin delivery and cause blood sugar fluctuations. Regularly check your infusion set to prevent issues.

26. Scar Tissue & Lipodystrophy: If you inject insulin, rotate your injection sites to avoid developing scar tissue, which can impact insulin absorption.

27. Intramuscular Insulin Delivery: Avoid injecting insulin into the muscle, as it may be absorbed too quickly, causing blood sugar fluctuations. Inject insulin into the fatty layer just beneath your skin.

28. Allergies: If you have food allergies, make sure you’re aware of how different foods affect your blood sugar levels. Also, some allergies can increase stress hormones, leading to blood sugar spikes.

29. A Higher BG Level (Glucotoxicity): High blood sugar can, in turn, cause blood sugar to rise further. Regular monitoring can help you prevent these spikes.

30. Periods (Menstruation): Hormonal fluctuations during your menstrual cycle can impact blood sugar levels. You may need to adjust your food intake or medication doses during this time.

31. Puberty: Hormonal changes during puberty can lead to increased insulin resistance. Regular monitoring and adjustment of medication doses can help manage blood sugar levels during this time.

32. Celiac Disease: If you have celiac disease, adhering to a gluten-free diet is important to avoid inflammation and nutrient malabsorption, which can impact blood sugar control.

33. Smoking: Smoking can increase insulin resistance and lead to higher blood sugar levels. Quitting smoking can significantly improve your blood sugar control.

Biological factors play a crucial role in diabetes management. As you navigate these complexities, remember that ongoing research and education are key to better understanding and managing diabetes. Support DRC to help us uncover new insights and provide valuable resources for those affected by diabetes. Your donation fuels vital research and contributes to a world of improved diabetes care. Take a step towards change – visit our website and donate today to make a meaningful difference in the diabetes community.

ENVIRONMENTAL

34. Expired Insulin: Always check the expiration date on your insulin. Expired insulin is less effective and can lead to higher blood sugar levels.

35. Inaccurate BG Reading: Regularly calibrate your blood glucose meter and check strips for accuracy to ensure your readings are accurate.

36. Outside Temperature: Extreme cold or hot temperatures can impact your blood sugar levels and how your body uses insulin. Try to stay in a moderate temperature environment when possible.

37. Sunburn: Sunburn can cause stress on the body, leading to higher blood sugar levels. Protect your skin when spending time in the sun.

38. Altitude: High altitudes can impact blood sugar control. If you’re traveling to a high-altitude area, monitor your blood sugar closely and discuss any necessary medication adjustments with your healthcare provider.

Navigate environmental challenges in diabetes management more effectively with ongoing research and education. Enhance our efforts at the Diabetes Research Connection. Your donation funds vital research and spreads key knowledge. Make a difference – visit our website and donate today for improved diabetes care.

BEHAVIOR & DECISIONS

39. More Frequent BG Checks: Frequent blood glucose checks can help you better understand your body’s patterns and make necessary adjustments to your diet or medication routine.

40. Default Options and Choices:

Plate/Bowl Size: The size of your plate or bowl can significantly influence portion control, a crucial factor in maintaining healthy blood sugar levels. Larger dishware tends to make us serve and consume more food than we need. By opting for smaller plates and bowls, you can naturally limit portion sizes, reducing overall carbohydrate intake and better managing your blood glucose levels.

Visual Prompts: Visual prompts play a significant role in our dietary choices. Keeping healthy food options visible and within reach encourages better food choices. Conversely, keeping high GI foods, like white bread and white rice, out of immediate sight can discourage unnecessary snacking, assisting in blood sugar control. A well-arranged fridge or pantry, with fresh fruits, vegetables, and whole grains at eye level, can serve as a constant visual prompt for healthy eating.

41. Decision-Making Biases:

Present Bias (Hyperbolic Discounting): Present bias refers to the tendency to prioritize immediate gratification over long-term benefits—a mindset that can sabotage diabetes management. For example, you might choose a sugary treat for immediate satisfaction, disregarding the long-term impact on your blood sugar levels. It’s essential to be aware of this bias and consciously make choices that favor long-term health.

Loss Aversion: This is the tendency to fear losses more than we value gains. In the context of diabetes, loss aversion might manifest as a fear of losing out on favorite foods. Shifting this mindset to focus on the gains, like improved health and energy levels when you control your blood sugar, can be a powerful motivator.

Negativity Bias: Negativity bias is the inclination to focus more on negative outcomes than positive ones. If you’ve had a bad experience with high or low blood sugar, you may become overly cautious or anxious. Remember, everyone with diabetes has good and bad days. Focus on the progress you’ve made and the tools you have to manage your condition.

Selective Matching: Selective matching involves making decisions based on memorable, though not necessarily representative, past experiences. For instance, if you had a hypoglycemic episode after a particular activity, you might avoid it completely. It’s important to remember that many factors can influence blood sugar levels, and what happened once might not happen again.

Representative Bias: Representative bias is the tendency to draw conclusions based on stereotypes or preconceptions. For example, assuming that all “sugar-free” products are good for blood glucose control can lead you astray. Always check the nutritional information, as these products can still contain other carbohydrates or unhealthy ingredients.

42. Family Relationships & Social Pressure: Communicate with your family and friends about your diabetes management needs. They can provide support and help you stick to your health goals.

Mastering behavior and decision-making is key in diabetes management. Enhance your understanding and strategies by contributing to DRC. Your donation aids in essential research and education, offering valuable insights for those affected by diabetes. Take a proactive step – visit our website and donate today to help advance our collective knowledge and improve diabetes care.

 

In conclusion, many factors contribute to the intricate balance of blood glucose regulation. Understanding these factors aids in managing diabetes effectively and maintaining optimal health. As always, our Diabetes Research Connection team encourages everyone, especially those diagnosed with type 1 or 2 diabetes, to educate themselves about the numerous factors affecting blood glucose. It’s not just about counting carbs; it’s about comprehending the complexity of your body and the many elements that can influence your blood glucose levels.

Adam Brown, a recognized contributor at diaTribe, meticulously compiled this list of 42 factors that influence blood glucose in Type 1 Diabetes. You heard it right, not one, not two, but 42 distinct variables. In his article, Adam states “I know what you’re thinking – 42 factors that affect blood glucose? Are you kidding?!”

The answer is yes, it is indeed a formidable task, but it’s essential to see it as a testament to the daily challenges we face and overcome.

To learn more about this AMAZING list and organization, click here.

If you struggle with meal planning, consider a diabetes specialist online nutritionist!

To support ongoing diabetes research and education, we invite you to visit the Diabetes Research Connection website. Your engagement and contributions are crucial in advancing our understanding and support for those living with diabetes. Whether you’re seeking more information or considering the guidance of a specialist, we’re here to help. Click here to join us in this journey towards better diabetes management and overall health.

 

 

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diabetes research, a modern lab with scientists analyzing various data on holographic screens, DNA strands, glucose molecules, and pancreas cells detailed, a futuristic and clean lab setting with soft blue light, highlighting the focus, dedication, and hopeful mood of the scientists, Photography, shot with a Nikon D850 using a 24-70mm lens at f/2.8, --ar 16:9 --v 5

The Fascinating History of Diabetes

Introduction to Mellitus

What’s Mellitus? Unraveling the threads of human history often reveals fascinating insights into our shared past. One such thread that has intricately woven itself into our narrative is diabetes.

This condition, which today impacts millions of lives globally, has a captivating origin and evolving story. From the first mention in ancient medical records to today, the diabetes history is both complicated and fascinating. We’ll go over type 1 diabetes history, and the history of diabetes type 2.

We are going to look a little into:

  • The history of diabetes mellitus, and why it was called that
  • How diabetes was treated in the 1900s
  • How diabetes was discovered in the 1600
  • How diabetes was diagnosed in the 1600
  • Alongside a lot of other interesting information

Most believe that diabetes was discovered in the 1600s, but we’ll look at how it may have been as early as the 2nd century.

On the diabetes history timeline the first recorded account goes back thousands of years into ancient history. Much like a cryptic riddle, diabetes presented itself as a puzzling condition to early healers. The beginnings of diabetes, or what we know today as diabetes mellitus, originated from early observations. Doctors noticed patients were urinating excessively and their urine had an unusual sweet taste.

The advent of the 17th century saw the scientific curiosity of the age tackling the mystery of diabetes. How was diabetes diagnosed in the 1600s? Would you be surprised to discover that it was the same way it had been diagnosed for thousands of years. Doctors would taste a patient’s urine to check if it was sweet, a key indicator of the disease.

But when was diabetes discovered exactly? And who were the pioneering minds behind these discoveries? We will guide you through type 1 and type 2 diabetes history. We’ll discuss the groundbreaking treatment methods, the first diabetes patient, and the incredible medical advances that have transformed diabetes management.

So join us as we trace the timeline of diabetes from its earliest known references to its modern understanding. We’ll explore the challenges, breakthroughs, and the relentless human spirit that has shaped the story of diabetes.

Diabetes in Ancient History: The Sweet Mystery

Diabetes, as we know it today, was a medical enigma to the physicians of ancient civilizations. Its mysterious nature and unique symptoms made it a distinctive condition, although its true cause remained unknown for centuries.

We don’t know when diabetes was first discovered but it was mentioned in Egyptian medical papyri dating back to 1500 BCE. These ancient documents describe a malady characterized by frequent urination, a symptom that is now associated with diabetes mellitus.

However, the term “diabetes” itself did not exist until around 250 BCE, when a Greek physician, Apollonius of Memphis, coined it. Derived from the Greek word “diabainein,” meaning “to pass through,” it referred to the excessive urination that marked the condition.

The term “mellitus”, which means “sweet like honey”, was added to diabetes because of the sweet taste of a patient’s urine. Ancient Greek doctors thought the urine of these patients tasted sweet. Doctor Thomas Willis named the disease “mellitus” in the 1600s.

He added this because there was another condition called “diabetes insipidus” that caused frequent urination without sweet urine. Even during Willis’ time, diagnosing diabetes still involved physicians tasting a patient’s urine to detect the presence of sugar.

Long story short, how was diabetes diagnosed in the 1600s? Pee being sweet… The history of type 1 diabetes is not very pleasant. We can only guess how they tested for diabetes in the old days.

These early references in diabetes mellitus origins underscore the evolving understanding of this complex condition in ancient times. While the methods might seem basic now, these observations laid the groundwork for future exploration and understanding of diabetes.

Evolution of Diabetes Understanding and Treatment: From Discovery to Innovations

How did diabetes start? In honesty we don’t know, we also don’t know for sure who discovered diabetes. In as early as the 2th century, Aretaeus of Cappadocia made a clear and accurate description.

The 19th century marked a new era in our understanding of diabetes. How was diabetes treated in the 1800s? Initially the same way since it was first discovered, through a low carbohydrate diet.

Then in 1889 the role of the pancreas in diabetes was established by German physicians Joseph von Mering and Oskar Minkowski. Their experiments involved removing the pancreas from a healthy dog, leading to the animal developing diabetes-like symptoms. This discovery underlined the pancreas’s role in blood sugar regulation.

However, the real breakthrough came in the 1920s with the discovery of insulin. Canadian doctor Banting and his assistant Best did experiments that changed diabetes treatment forever. They successfully extracted insulin, a hormone produced by the islets of Langerhans in the pancreas. This hormone is important for controlling blood sugar levels and changed how diabetes was diagnosed in the 1920s.

Their groundbreaking work led to the first successful insulin treatment of a diabetes patient in 1922. Leonard Thompson, a 14-year-old boy, became the first patient to receive an insulin injection, significantly improving his health. Banting and Macleod won the Nobel Prize in Medicine in 1923 for their important discovery.

As the 20th century progressed, further advances were made in diabetes diagnosis and treatment. By the 1960s, self-monitoring of blood glucose levels had become a reality. The development of glucose monitors and insulin pumps offered people with diabetes more control over their health. These contributed heavily to how diabetes was diagnosed in the 1960s.

The 1980s brought another milestone with the introduction of human insulin. Before this, insulin was primarily extracted from pigs and cattle. Human insulin made with DNA technology has helped people with diabetes by improving treatment and reducing side effects.

Humans are determined to learn and find solutions. This is evident in the study of diabetes and its treatment. The study has progressed from finding sugar in urine to using insulin. The history of diabetes timeline has important milestones that help us understand and manage this complex condition.

The Modern History of Diabetes: A New Era of Treatment and Technology

With the discovery of human insulin, the world of diabetes treatment entered a new era. As the 20th century progressed, technology became an increasingly important ally in the fight against diabetes.

Insulin pumps in the 1970s delivered insulin under the skin, acting like a healthy pancreas. This not only improved blood glucose control but also provided people living with diabetes greater flexibility and quality of life.

The 1980s brought blood glucose meters. Devices for monitoring blood sugar levels at home are essential for managing diabetes effectively. In the 90s, these devices were common. By the 2000s, they became smaller, faster, and more precise.

The next major breakthrough in diabetes management came in the form of Continuous Glucose Monitoring (CGM) systems in the early 2000s. These devices monitor blood sugar levels continuously, both during the day and at night. They have significantly enhanced the management of both type 1 and type 2 diabetes.

The Distinct Paths of Type 1 and Type 2 Diabetes

Even though Type 1 and Type 2 diabetes share a common name, their causes, development, and treatment approaches significantly differ. These two types of diabetes have distinct histories and pathways, contributing uniquely to our overall understanding of diabetes as a condition.

The History of Type 2 Diabetes – Type 2 diabetes is largely a disease of lifestyle and usually develops later in life. Type 2 diabetes was first described in the 1930s, although its history is not as well-documented as Type 1 diabetes. It was recognized as a distinct condition, different from Type 1 diabetes, that generally affected adults and wasn’t dependent on insulin. The disease likely existed long before but was not distinguished from other forms of diabetes.

In the past, Type 2 diabetes was treated with diet and exercise. But now, the way it is managed has improved. In the 1950s, drugs like metformin were introduced to help fight Type 2 diabetes by lowering blood sugar levels.

Type 1 and Type 2 Diabetes both cause high blood sugar, but their causes are different. Type 1 is a condition that starts in childhood. It happens when the body’s immune system attacks and destroys cells in the pancreas that make insulin.

On the other hand, Type 2 diabetes typically develops in adults and is often linked to obesity and a sedentary lifestyle. The body may not use insulin properly or produce enough. In order to control it, lifestyle changes, pills, or insulin injections may be necessary.

Both types have different histories, understanding, and treatment. They are distinct conditions and need separate approaches in management and research.

The story of diabetes is a testament to human resilience and the power of scientific discovery. Its mysterious origins in ancient history to the revolutionary discovery of insulin by Frederick Banting and Charles Herbert Best. Insulin pumps, glucose monitoring, and diabetes management have improved a lot with groundbreaking technologies and our knowledge. Yet, the journey is far from over, as researchers worldwide continue to seek even better treatments and, ultimately, a cure for mellitus.

Conclusion: The Journey Continues

Diabetes history has seen many discoveries, from ancient times to modern glucose monitors and insulin pumps. The narrative of diabetes is an inspiring testament to human resilience and innovation.

The work of Apollonius of Memphis, Frederick Grant Banting, and Charles Herbert Best has changed our understanding of diabetes. Their research paved the way for the advances of diabetic management for those living with the condition. Moreover, the story of the first diabetes patient, Leonard Thompson, demonstrates the tangible impact of scientific discovery on human lives.

However, the story of diabetes is far from finished. Despite the progress we’ve made, the global prevalence of diabetes continues to rise, underscoring the need for ongoing research and innovation. At the Diabetic Research Connection we support cutting-edge research and raise funding for the next generation of discoveries in diabetes.

We invite you to be part of our ongoing journey as we try to expand our understanding of diabetes. Ultimately paving the way for effective therapies and even a cure. The history of diabetes is still being written, and together, we can play a crucial role in shaping its future.

Honorable Mention

Banting and Macleod were awarded a nobel prize for their discovery of insulin. This makes them one of the first persons to receive a noble prize for diabetes-related science.

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Potential Benefits of Incorporating C4H11N5 in Type 1 Diabetes Treatment

Metformin: A Potential Game-Changer in Type 1 Diabetes Management

The journey of managing diabetes is a complex one, impacted by a myriad of factors affecting blood sugar levels. One such factor is the type of medication utilized. For people living with type 2 diabetes, Metformin is a well-known medication, typically employed to regulate blood sugar levels. Recently, however, it has emerged into the spotlight for a different reason – its potential benefits in treating type 1 diabetes. This surprising finding can be traced back to a recent study examining Metformin’s impact on vascular health, presenting a new ray of hope for healthcare professionals and individuals diagnosed with type 1 diabetes. This novel application is especially noteworthy, as those living with type 1 diabetes frequently face an elevated risk of cardiovascular disease – a life-threatening condition if left unchecked.

The Groundbreaking Study

Researchers undertook a meticulously conducted double-blind, randomized, placebo-controlled trial. The participants were 90 children aged 8 to 18, all hailing from South Australia, and each one had been navigating life with type 1 diabetes for at least six months. These participants were split into two equally sized groups. One group received Metformin, while the other was given a placebo.

In addition to administering the trial’s medication, the researchers paid close attention to a few crucial parameters that are known to affect blood sugar levels. HbA1C, which provides an overview of blood sugar control over the past 2-3 months, insulin dose, and BMI were meticulously recorded. The team also incorporated the use of a continuous glucose monitoring (CGM) system, an advanced technology providing real-time glucose readings, an invaluable tool in achieving a granular level of insight into blood sugar control.

Dietary Factors and Blood Sugar Control

Throughout the trial, the participants’ diet was carefully observed, focusing on foods that vary in their glycemic index (GI), a measure that ranks carbohydrate-containing foods by how much they boost blood sugar levels. Foods with a high GI, including white rice and white bread, have a significant impact on blood glucose levels, causing spikes that can be detrimental if not managed effectively.

The importance of maintaining a balance in blood sugar levels was also emphasized throughout the trial. The target range for each participant was meticulously defined, aiming to keep it above 70mg/dl to prevent hypoglycemia (low blood sugar), and below a specified threshold to avoid hyperglycemia (high blood sugar). Frequent blood glucose monitoring played a critical role in maintaining this equilibrium, with the participants encouraged to use their blood glucose meter consistently.

Results and Potential Implications

The trial produced promising results. Over the year, the Metformin group showed distinct improvement in vascular function over the placebo group. This was most noticeable at the three-month interval. Interestingly, this was also when a significant decrease in HbA1C levels was recorded, indicating better control of blood sugar. By the 12-month mark, although the difference was lower, it remained significant. Furthermore, the Metformin group required less insulin, suggesting a decrease in insulin resistance – an encouraging development.

Another noteworthy finding was that children with above-average BMIs who were taking Metformin showed a marked improvement in vascular smooth muscle function. This improvement is indicative of better overall vascular health, which, in turn, can help reduce the risk of cardiovascular disease – a common complication for those living with type 1 diabetes.

While these findings offer hope for more diverse treatment options for people with type 1 diabetes, it’s important to note that the study didn’t run long enough to determine potential changes in vascular structure, only vascular function. Nevertheless, the potential implications are exciting.

Conclusion: Hope for the Future

If Metformin can indeed help in better managing type 1 diabetes, this could herald a new era in diabetes care. Improved diabetes management could lead to a higher quality of life for individuals living with the condition. With more research, the question of how to control blood sugar could become easier to answer, particularly if Metformin proves to be an effective part of the solution.

As we move forward, this type of groundbreaking study underlines the critical importance of continued research in the field of diabetes. At Diabetes Research Connection, we are committed to supporting advancements like this by funding novel research projects. We believe in the power of scientific discovery to transform lives and improve the future for those living with diabetes. We invite you to join us on this journey and support this life-changing mission. Visit https://diabetesresearchconnection.org to learn more about our initiatives and see how you can make a difference. Together, we can chart a brighter path toward managing, and ultimately curing, diabetes.

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Qualifying for Social Security Benefits With Diabetes Complications

Guest Post by Disability Benefits Help

If you’re unable to manage your diabetes with lifestyle changes and medication, you may be eligible for assistance. The Social Security Administration (SSA) offers monthly disability benefits for people who are unable to work due to an illness or injury that will last for at least 12 months. While it is challenging to qualify with diabetes, those with significant complications may be eligible for help.

Medical Eligibility Via the Blue Book

The SSA uses its own medical guidebook of eligibility criteria, known colloquially as the Blue Book, when deeming eligibility status. Diabetes is not listed as a disabling condition in the Blue Book, but some of its complications are. Here are a couple of listings you may be able to qualify under:

Amputation

An amputation alone also will not qualify for disability benefits, but you will be eligible if you can meet any one of the following criteria:

  • You have both hands amputated
  • You have two limbs amputated but you’re unable to walk without use of two crutches, a walker, or a wheelchair
  • You have an amputation at the hip

If your mobility is severely limited, you should be able to qualify under the amputation listing. Keep in mind that this listing is for people who are unable to successfully use artificial limbs. If you’re able to walk with an artificial limb, you will not qualify here.

Neuropathy

Neuropathy will also qualify under the Blue Book. The first listing states that you’ll be eligible if you have neuropathy in at least two limbs and it makes it impossible for you to either stand from a seated position, balance while standing upright, or walk without using crutches, a walker, or a wheelchair.

If you still have some mobility but it’s affecting your ability to work, you will also qualify if you have significant difficulty with any one of the following areas of intellectual function:

  • Understanding, remembering, and applying information
  • Interacting with others in a work setting
  • Concentrating and completing tasks
  • “Adapting oneself,” which means controlling emotions in a work setting

The entire Blue Book can be found online, so you can review it with your doctor to determine if you qualify. There are dozens of listings that may be relevant for people with diabetes, including cardiovascular disorders, additional mobility problems, and more.

Starting Your Application

The easiest way to apply for disability is online on the SSA’s website. If you’d prefer, you can also apply in person with the assistance from a Social Security representative. Call the SSA toll free at 1-800-772-1213 to make an appointment to apply in person at your closest SSA office.

It should take three to five months to hear back from the SSA regarding your claim. The more disabilities and complications of diabetes you list on your application, the better your odds of approval.

Resources:

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Insurance Gaps Put Individuals with Type 1 Diabetes at Increased Risk

Over the past few years, health insurance has gone through some major changes. Since type 1 diabetes requires constant monitoring and daily management with insulin, having insurance coverage is essential to help offset costs and promote effective self-care. A recent study found that individuals who experience gaps in private healthcare insurance coverage may be at greater risk for health crises.

The study involved data collected from approximately 169,000 adults with type 1 diabetes between the ages of 19 and 64 during the time period of early 2001 to mid-2015. Researchers evaluated this data and found that visits to the emergency room, hospital, or urgent care were five times more likely when patients regained coverage after a gap in insurance of 30 to 60 days. When the coverage gap expanded to 91 to 120 days, those individuals were seven times more likely to visit the emergency room, hospital, or urgent care.

These visits can be incredibly costly, but risk can be reduced with consistent insurance coverage and self-care under the direction of a physician. The study found that young adults – those in their 20s and 30s – were more likely to experience gaps in coverage than middle-aged and older adults. What part of the country individuals resided in played a role as well, with the north-central and southern parts of the United States seeing higher rates of gaps.

Since type 1 diabetes affects approximately 1.25 million Americans, it is essential that quality care and insurance coverage are available to support improved health and well-being and reduce the risk of preventable health crises.

The Diabetes Research Connection (DRC) is passionate about exploring various aspects of type 1 diabetes from prevention and treatment to potential cures and improved quality of life. The DRC provides valuable funding to support novel research studies regarding this condition. To learn more about current projects or donate to these efforts, visit Our Projects.

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Breaking Down the Prevalence of Type 1 Diabetes

Diabetes affects people of all ages and races throughout the United States, but just how many people are impacted? According to a self-report study of 33,028 adults with a response rate of 54.3%, approximately 21 million adults (8.6%) in the United States were living with type 2 diabetes in 2016, and approximately 1.3 million (0.55%) were living with type 1 diabetes.

The study, conducted by the Centers for Disease Control and Prevention (CDC) asked participants a variety of questions regarding being diagnosed with diabetes and what methods were used to manage it. Responses were classified as type 1, type 2, or “other” type of diabetes. There were 182 participants who reported having type 1 diabetes but did not claim to take any type of insulin, so they were categorized as type 2 respondents. Out of the 33,028 participants, 3,519 reported having diabetes, and 211 of those reported having type 1 diabetes. The study also found that T1D was more prevalent in men than women (0.64% vs. 0.46%), and as well as in non-Hispanic whites versus Hispanics (0.67% and 0.22% respectively).

Study authors hope that “knowledge about national prevalence of type 1 and type 2 diabetes might facilitate assessment of the long-term cost-effectiveness of public health interventions and policies aimed at improving diabetes management and help to prioritize national plans for future type-specific health services.”

Though it may seem like a small percentage who have T1D, it is still more than a million people who struggle each day with this disease, and more than a million people who would benefit from advanced research and treatment options. The Diabetes Research Connection seeks to further knowledge, research, and interventions regarding type 1 diabetes as well and supports novel research studies focused on this condition. Early career scientists can receive valuable funding through the DRC to support their research projects. Click to learn more about current projects and provide support.

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Could Patients with Type 1 Diabetes Benefit from Medical Alert Systems?

Patients living with type 1 diabetes do a whole lot of balancing. Aside from having to always keep their blood sugar and insulin levels in check, they also need to make sure that they strike the perfect balance between the medication they take, the food they eat and the exercises they do. The good news, however, is that it’s becoming a lot easier for patients to keep track of their levels thanks to emerging diabetes technologies. Moreover, companies are getting closer to perfecting closed-loop systems that aim to automate as much of the monitoring and treatment processes as possible so the patient can focus on things that they care about. Does this mean, therefore, that there’s no longer any need for patients to invest in medical alert systems? Well, the short answer is not quite.

Consider the possible complications

While the symptoms of type 1 diabetes are quite manageable, the complications can be a bit trickier. Aside from eye, nerve and kidney damage, it can also cause heart and blood vessel issues, which could lead to heart attacks. Needless to say, whenever a heart attack happens, time is always of the essence. The faster the patient is given proper treatment, the bigger their chances of survival. This is where the ability to quickly contact emergency services comes in. Medical alert systems make it possible for patients to easily call for help even if they are alone or, for some reason, incapacitated.

They’re meant to augment the patient’s existing tools

Again, living with type 1 diabetes requires the patient to keep track and balance a lot of things. This means that a simple change in one thing—like the type of exercises they do or the food they eat—could easily change their body’s overall dynamic. This, of course, could lead to all sorts of unforeseen issues—which is another reason why it’s crucial for patients to have some form of medical alert system in their diabetes toolkits at all times.

Readiness is key

It’s definitely becoming so much easier for patients with type 1 diabetes to live with their condition. With modern tools for monitoring and treatment becoming more and more sophisticated, the risk for serious complications has gone down significantly. This, however, does not mean that it’s okay to be complacent. At the end of the day, medical alert systems still give patients a significantly better fighting chance in case something goes wrong, and that’s definitely not an opportunity anyone should pass on.

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42 Factors that affect BG

42 Factors That Affect Blood Glucose

42 Factors That Affect Blood Glucose

Welcome to the Diabetes Research Connection, your trusted platform for valuable insights on diabetes management. Here we explore the above, “42 Factors That Affect BG”. Understanding these factors is crucial for anyone diagnosed with type 1 diabetes, health care providers, family and friends about how our bodies regulate blood sugar levels.

FOOD

1. Carbohydrate Quantity: Understanding carbohydrate intake is important for those with diabetes. Consider portion control and learn to read food labels. Remember, balancing carbohydrates with other food groups can help to stabilize blood sugar levels.

2. Carbohydrate Type: Opt for complex carbohydrates such as whole grains, fruits, and vegetables. These types are digested more slowly, preventing sudden blood sugar spikes.

3. Fat: Limit the amount of saturated and trans fats, which can lead to insulin resistance. Instead, choose heart-healthy unsaturated fats found in foods like avocados, nuts, and olive oil.

4. Protein: Include lean protein sources like chicken, fish, tofu, or lentils into your meals. Protein doesn’t raise blood sugar levels significantly and can help to keep you feeling satiated.

5. Caffeine: Monitor your body’s reaction to caffeine. Some people with diabetes find that caffeine causes blood sugar fluctuations. If that’s the case, reduce your caffeine intake.

6. Alcohol: If you choose to drink alcohol, do so in moderation and never on an empty stomach, as it can cause hypoglycemia. Choose low-sugar mixers to avoid blood sugar spikes.

7. Meal Timing: Regular meal and snack times can prevent blood sugar swings. Avoid skipping meals or eating late at night.

8. Dehydration: Make sure you’re drinking plenty of water throughout the day. Dehydration can negatively impact blood sugar levels.

9. Personal Microbiome: A healthy gut microbiome is believed to influence blood sugar control. Incorporate probiotic-rich foods like yogurt and fermented foods into your diet.

MEDICATION

10. Medication Dose: Always take the correct dosage of your medications as prescribed by your healthcare provider. Any changes can cause fluctuations in your blood sugar levels.

11. Medication Timing: Take your medications at the same time every day. This consistency can greatly help in managing your blood sugar levels.

12. Medication Interactions: Be aware that certain medications can interact with your diabetes medication and impact your blood sugar levels. Always inform your healthcare provider about all the medications you’re taking.

13. Steroid Administration: Steroids can cause increased blood sugar levels. If you’re prescribed a steroid, monitor your blood sugar closely and report any prolonged high readings to your healthcare provider.

14. Niacin (Vitamin B3): While niacin is important for overall health, it can raise blood sugar levels. Make sure you are getting an appropriate amount, and monitor your blood sugar if you take a supplement.

ACTIVITY

15. Light Exercise: Regular light exercise, such as walking or gentle yoga, can help control blood sugar levels. Try to be active every day, but remember to monitor your blood sugar before, during, and after exercise.

16.High Intensity & Moderate Exercise: Exercise is key in diabetes management. High-intensity workouts like HIIT can improve insulin sensitivity, while moderate activities like brisk walking help regulate glucose levels. However, monitor your blood sugar before, during, and after exercise to avoid hyperglycemia or hypoglycemia. Always consult your healthcare provider before starting a new fitness regimen.

17. Level of Fitness/Training: Your overall fitness level can impact how your body uses insulin. Regular exercise can improve insulin sensitivity and help manage blood sugar levels. However, intense training may cause short-term blood sugar spikes, so monitor your levels and adjust your food intake or insulin dosage as needed.

18. Time of Day: Blood sugar can fluctuate throughout the day. Monitoring your blood sugar levels at various times can help you understand your body’s patterns and adjust your routine accordingly.

19. Food & Insulin Timing: For those taking insulin, coordinating your meals and insulin dosage is crucial. The timing will depend on your specific needs and the type of insulin you’re using.

BIOLOGICAL

20. Too Little Sleep: Lack of sleep can disrupt your body’s insulin usage. Try to get at least 7-9 hours of sleep each night to help regulate your blood sugar.

21. Stress & Illness: Stress and illness can cause blood sugar levels to spike. Find stress management techniques that work for you, such as meditation or deep breathing exercises, and remember to monitor your blood sugar closely when you’re sick.

22. Recent Hypoglycemia: If you’ve recently experienced a bout of hypoglycemia, your body may release hormones that cause your blood sugar to rise. It’s important to monitor your blood sugar levels closely to prevent a “rebound” high.

23. During-Sleep Blood Sugars: Overnight blood sugar levels can fluctuate. Consider using a continuous glucose monitor to track your levels while you sleep.

24. Dawn Phenomenon: This is a surge in hormones that happens in the early morning, often causing an increase in blood sugar. Adjusting medication or food intake before bed can help manage this.

25. Infusion Set Issues: If you use an insulin pump, issues with the infusion set, like kinks or blockages, can affect insulin delivery and cause blood sugar fluctuations. Regularly check your infusion set to prevent issues.

26. Scar Tissue & Lipodystrophy: If you inject insulin, rotate your injection sites to avoid developing scar tissue, which can impact insulin absorption.

27. Intramuscular Insulin Delivery: Avoid injecting insulin into the muscle, as it may be absorbed too quickly, causing blood sugar fluctuations. Inject insulin into the fatty layer just beneath your skin.

28. Allergies: If you have food allergies, make sure you’re aware of how different foods affect your blood sugar levels. Also, some allergies can increase stress hormones, leading to blood sugar spikes.

29. A Higher BG Level (Glucotoxicity): High blood sugar can, in turn, cause blood sugar to rise further. Regular monitoring can help you prevent these spikes.

30. Periods (Menstruation): Hormonal fluctuations during your menstrual cycle can impact blood sugar levels. You may need to adjust your food intake or medication doses during this time.

31. Puberty: Hormonal changes during puberty can lead to increased insulin resistance. Regular monitoring and adjustment of medication doses can help manage blood sugar levels during this time.

32. Celiac Disease: If you have celiac disease, adhering to a gluten-free diet is important to avoid inflammation and nutrient malabsorption, which can impact blood sugar control.

33. Smoking: Smoking can increase insulin resistance and lead to higher blood sugar levels. Quitting smoking can significantly improve your blood sugar control.

ENVIRONMENTAL

34. Expired Insulin: Always check the expiration date on your insulin. Expired insulin is less effective and can lead to higher blood sugar levels.

35. Inaccurate BG Reading: Regularly calibrate your blood glucose meter and check strips for accuracy to ensure your readings are accurate.

36. Outside Temperature: Extreme cold or hot temperatures can impact your blood sugar levels and how your body uses insulin. Try to stay in a moderate temperature environment when possible.

37. Sunburn: Sunburn can cause stress on the body, leading to higher blood sugar levels. Protect your skin when spending time in the sun.

38. Altitude: High altitudes can impact blood sugar control. If you’re traveling to a high-altitude area, monitor your blood sugar closely and discuss any necessary medication adjustments with your healthcare provider.

BEHAVIOR & DECISIONS

39. More Frequent BG Checks: Frequent blood glucose checks can help you better understand your body’s patterns and make necessary adjustments to your diet or medication routine.

40. Default Options and Choices:

Plate/Bowl Size: The size of your plate or bowl can significantly influence portion control, a crucial factor in maintaining healthy blood sugar levels. Larger dishware tends to make us serve and consume more food than we need. By opting for smaller plates and bowls, you can naturally limit portion sizes, reducing overall carbohydrate intake and better managing your blood glucose levels.

Visual Prompts: Visual prompts play a significant role in our dietary choices. Keeping healthy food options visible and within reach encourages better food choices. Conversely, keeping high GI foods, like white bread and white rice, out of immediate sight can discourage unnecessary snacking, assisting in blood sugar control. A well-arranged fridge or pantry, with fresh fruits, vegetables, and whole grains at eye level, can serve as a constant visual prompt for healthy eating.

41. Decision-Making Biases:

Present Bias (Hyperbolic Discounting): Present bias refers to the tendency to prioritize immediate gratification over long-term benefits—a mindset that can sabotage diabetes management. For example, you might choose a sugary treat for immediate satisfaction, disregarding the long-term impact on your blood sugar levels. It’s essential to be aware of this bias and consciously make choices that favor long-term health.

Loss Aversion: This is the tendency to fear losses more than we value gains. In the context of diabetes, loss aversion might manifest as a fear of losing out on favorite foods. Shifting this mindset to focus on the gains, like improved health and energy levels when you control your blood sugar, can be a powerful motivator.

Negativity Bias: Negativity bias is the inclination to focus more on negative outcomes than positive ones. If you’ve had a bad experience with high or low blood sugar, you may become overly cautious or anxious. Remember, everyone with diabetes has good and bad days. Focus on the progress you’ve made and the tools you have to manage your condition.

Selective Matching: Selective matching involves making decisions based on memorable, though not necessarily representative, past experiences. For instance, if you had a hypoglycemic episode after a particular activity, you might avoid it completely. It’s important to remember that many factors can influence blood sugar levels, and what happened once might not happen again.

Representative Bias: Representative bias is the tendency to draw conclusions based on stereotypes or preconceptions. For example, assuming that all “sugar-free” products are good for blood glucose control can lead you astray. Always check the nutritional information, as these products can still contain other carbohydrates or unhealthy ingredients.

42. Family Relationships & Social Pressure: Communicate with your family and friends about your diabetes management needs. They can provide support and help you stick to your health goals.

In conclusion, many factors contribute to the intricate balance of blood glucose regulation. Understanding these factors aids in managing diabetes effectively and maintaining optimal health. As always, our Diabetes Research Connection team encourages everyone, especially those diagnosed with type 1 or 2 diabetes, to educate themselves about the numerous factors affecting blood glucose. It’s not just about counting carbs; it’s about comprehending the complexity of your body and the many elements that can influence your blood glucose levels.

Adam Brown, a recognized contributor at diaTribe, meticulously compiled this list of 42 factors that influence blood glucose in Type 1 Diabetes. You heard it right, not one, not two, but 42 distinct variables. In his article, Adam states “I know what you’re thinking – 42 factors that affect blood glucose? Are you kidding?!”

The answer is yes, it is indeed a formidable task, but it’s essential to see it as a testament to the daily challenges we face and overcome.

To learn more about this AMAZING list and organization, click here.

If you struggle with meal planning, consider a diabetes specialist online nutritionist!

 

 

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Islets

Stem-Cell Derived Therapy for Type 1 Diabetes Funded to Move Forward

Scientists have been exploring many options for treating and potentially curing type 1 diabetes (T1D) in recent years. From examining the role of gut cells to creating an artificial pancreas, the studies have been diverse. Some challenges that they have faced are undesirable side effects, short-term effects, the need for immune suppression, and continued destruction of insulin-producing cells.

However, Semma Therapeutics recently secured $114 million in Series B financing to move forward with a program using encapsulated stem cell-derived islets to treat and potentially cure T1D. This financing was made possible through investments from multiple partners and investors. It will be used to advance the stem-cell derived therapy through clinical proof-of-concept in patients.

The technology and processes used by Semma have the ability to create billions of insulin-producing beta cells that perform in the same way these cells do when naturally produced by the body. However, these cells are combined with an innovative cell delivery technology that protects them from being destroyed by the body’s immune system. Ideally, this would enable them to continue regulating blood sugar while reducing the risk of complications and the need for constant blood sugar monitoring and insulin injections.

According to Semma Therapeutics Founder and Board Observer Douglas Melton, “Semma’s scientists have very effectively dedicated themselves to systems that reliably generate cells indistinguishable from human pancreatic beta cells and to the invention of novel devices that are immunologically protective and surgically practical. We’re very encouraged and excited about the potential this program has for diabetic patients and their families.”

The Diabetes Research Connection is eager to see how this program could impact the lives of those living with T1D, as well as the progress and direction of treatment options moving forward. The Diabetes Research Connection is not connected to this project, but raises funds to support early career scientists in conducting novel research in preventing, treating, and curing T1D, as well as improving quality of life for individuals with the disease. Click to learn more about current projects and provide support.

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Artificial Pancreas

How Technology is Changing Diabetes Care and Treatment

Despite years of research and clinical trials, no cure for type 1 diabetes exists yet. However, how the disease is managed and treated has changed, leading to vast improvements in quality of life. Many individuals are better able to track their blood sugar and administer insulin more effectively to reduce instances of hypoglycemia and other complications. A recent article explores how technology has impacted current research for type 1 diabetes.

For years, researchers were focused on developing immunotherapies to try to treat T1D at its source. With this type of diabetes, the immune system attacks and destroys insulin-producing beta cells from the pancreas. The goal was to either reverse the disease or stop it from developing in the first place. Today, researchers have shifted their focus. Instead of trying to figure out how to prevent diabetes, some scientists are working to improve how patients live with the disease. This has involved major leaps in medicine including attempts at developing an artificial pancreas system that would function similar to the body’s own pancreas to regulate blood sugar.

Over the years, researchers have experimented with a variety of immune therapies trying to find an approach that could treat diabetes without a host of unpleasant side effects. This has been a difficult process and not yet produced a significantly effective treatment. However, there have continued to be technological advances that have improved how patients manage diabetes. It is easier than ever to quickly test blood sugar, and some patients even have continuous glucose monitors that send information to their smartphone and alert to low blood sugar. There have also been many improvements in more accurate dosing and administering insulin.

In 2016, scientists made progress toward creating an “artificial pancreas” system. It combined a continuous glucose monitor and insulin pump to modulate insulin delivery based on data over time. It is not yet fully automated, however, because patients still must calculate their insulin dosage during meal times. But it did have benefits for reducing hypoglycemia overnight. This technology has opened doors for others to begin testing different approaches for creating a fully automated insulin delivery artificial pancreas system. While not a “cure” for type 1 diabetes, it could help improve management of the disease while decreasing the burden on patients.

There is still a great deal of research and work to be done before this type of treatment comes to fruition. And once it exists, there is no guarantee that every patient would choose to use it, just like not all patients choose to have continuous glucose monitors. But it would be another option that exists and could potentially have a significant impact on people’s lives.

The Diabetes Research Connection recognizes the life-changing impact that a T1D diagnosis has, and supports early career scientists in moving forward with novel research projects focused on preventing, curing, or managing type 1 diabetes. Through donations from individuals, corporations, and foundations, research funding is made possible. Click to learn more about current projects and provide support.

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OUR PROJECTS

See our approved research projects and campaigns.

Role of the integrated stress response in type 1 diabetes pathogenesis
In individuals with type 1 diabetes (T1D), the insulin-producing beta cells are spontaneously destroyed by their own immune system. The trigger that provokes the immune system to destroy the beta cells is unknown. However, accumulating evidence suggest that signals are perhaps first sent out by the stressed beta cells that eventually attracts the immune cells. Stressed cells adapt different stress mitigation systems as an adaptive response. However, when these adaptive responses go awry, it results in cell death. One of the stress response mechanisms, namely the integrated stress response (ISR) is activated under a variety of stressful stimuli to promote cell survival. However, when ISR is chronically activated, it can be damaging to the cells and can lead to cell death. The role of the ISR in the context of T1D is unknown. Therefore, in this DRC funded study, we propose to study the ISR in the beta cells to determine its role in propagating T1D.
Wearable Skin Fluorescence Imaging Patch for the Detection of Blood Glucose Level on an Engineered Skin Platform
zhang
A Potential Second Cure for T1D by Re-Educating the Patient’s Immune System
L Ferreira
Validating the Hypothesis to Cure T1D by Eliminating the Rejection of Cells From Another Person by Farming Beta Cells From a Patient’s Own Stem Cells
Han Zhu
Taming a Particularly Lethal Category of Cells May Reduce/Eliminate the Onset of T1D
JRDwyer 2022 Lab 1
Can the Inhibition of One Specific Body Gene Prevent Type 1 Diabetes?
Melanie
Is Cholesterol Exacerbating T1D by Reducing the Functionality and Regeneration Ability of Residual Beta Cells?
Regeneration Ability of Residual Beta Cells
A Call to Question… Is T1D Caused by Dysfunctionality of Two Pancreatic Cells (β and α)?
Xin Tong
Novel therapy initiative with potential path to preventing T1D by targeting TWO components of T1D development (autoimmune response and beta-cell survival)
flavia pecanha